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Uterine fibroids

C10orf95-AS1 · rs538679208

Where this position leads

Condition: Uterine Fibroids

rs538679208 Condition: Uterine Fibroids Uterine Fibroids Condition rs538679208 rs538679208 C10orf95-AS1

What the study found

Who was studied 53,711 European ancestry female cases, 380,441 European ancestry female controls.

The effect Each copy of the A allele shifted the measure 0.161 higher (95% confidence interval 0.11-0.21); p = 4 × 10−11.

Where it sits Chromosome 10, band 10q24.32 — in an intron of C10orf95-AS1.

What each result means

A/A Two copies of the version the research linked to Uterine fibroids. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Uterine fibroids. That is a smaller link than two copies.
T/T No copy of the version the research linked to Uterine fibroids. This is the starting point the study compared everyone against.
Source

Questions about rs538679208

What is rs538679208?

rs538679208 is a single position in the genome, in or near the C10orf95-AS1 gene. Published research associates it with uterine fibroids. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs538679208 linked to?

On MyGeneLog this position is linked to Uterine Fibroids. The research behind each link, and its sources, are set out on that condition page.

Does having rs538679208 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs538679208 come from?

GWAS Catalog, Nature communications 2025, PMID:40050615. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Uterine fibroids (rs538679208). MyGeneLog™. https://www.mygenelog.com/variants/rs538679208

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