1 361228123215Reads by AI crawlersClaude1ChatGPT2Google · Gemini0Perplexity2Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others15Total36Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 59,357 British ancestry males, 66,310 British ancestry females.
The effect
Each copy of the C allele shifted the measure 0.314 higher (95% confidence interval 0.21-0.41); p = 7 × 10−10.
How common The C allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 9, band 9q21.12 — in an intron of SMC5.
What each result means
C/CTwo copies of the version the research linked to Age at first sexual intercourse. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Age at first sexual intercourse. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Age at first sexual intercourse. This is the starting point the study compared everyone against.
rs538498277 is a single position in the genome, in or near the SMC5 gene. Published research associates it with age at first sexual intercourse. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs538498277 linked to?
On MyGeneLog this position is linked to Age at First Sexual Intercourse. The research behind each link, and its sources, are set out on that condition page.
Does having rs538498277 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs538498277 come from?
GWAS Catalog, Nat Genet 2016, PMID:27089180. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 361228123215Reads by AI crawlersClaude1ChatGPT2Google · Gemini0Perplexity2Meta AI8Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others15Total36Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Age at first sexual intercourse (rs538498277). MyGeneLog™. https://www.mygenelog.com/variants/rs538498277