Sensitive

Colorectal cancer

near FAM135B · rs538113020

Where this position leads

Condition: Colorectal Cancer

rs538113020 Condition: Colorectal Cancer Colorectal Cancer Condition rs538113020 rs538113020 near FAM135B

What the study found

Who was studied 4,988 European ancestry cases, 310,272 European ancestry controls.

The effect Each copy of the C allele shifted the measure 1.15 higher (95% confidence interval 0.75-1.54); p = 2 × 10−8.

Where it sits Chromosome 8, band 8q24.23 — between genes, 128.4 kb from FAM135B.

What each result means

C/C Two copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
Source

Questions about rs538113020

What is rs538113020?

rs538113020 is a single position in the genome, in or near the near FAM135B gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs538113020 linked to?

On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs538113020 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs538113020 come from?

GWAS Catalog, Scientific reports 2024, PMID:38538606. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Colorectal cancer (rs538113020). MyGeneLog™. https://www.mygenelog.com/variants/rs538113020

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