0 6123Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 211 African American or Afro-Caribbean cases, 121,521 African American or Afro-Caribbean controls, 1,218 European ancestry cases, 449,047 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 4.37 lower (95% confidence interval 4.36-4.38); p = 1 × 10−11.
How common The T allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 3, band 3q29 — in an intron of LINC02028.
What each result means
C/CNo copy of the version the research linked to Pernicious anemia (PheCode 281.11). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Pernicious anemia (PheCode 281.11). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Pernicious anemia (PheCode 281.11). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs537837866
What is rs537837866?
rs537837866 is a single position in the genome, in or near the LINC02028 gene. Published research associates it with pernicious anemia (phecode 281.11). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs537837866 linked to?
On MyGeneLog this position is linked to Pernicious Anemia. The research behind each link, and its sources, are set out on that condition page.
Does having rs537837866 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs537837866 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 6123Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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