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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 45,502 European ancestry cases, 96,601 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 1.35 higher (95% confidence interval 1.08-1.62); p = 1 × 10−21.
How common The G allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 5, band 5p15.33 — a synonymous change in PDCD6-AHRR.
What each result means
A/ANo copy of the version the research linked to Hearing difficulty. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Hearing difficulty. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Hearing difficulty. That is the strongest link of the three results. A link in a study is not a diagnosis.
European journal of human genetics : EJHG · 2023 · PMID 36788145
Questions about rs537688122
What is rs537688122?
rs537688122 is a single position in the genome, in or near the PDCD6-AHRR gene. Published research associates it with hearing difficulty. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs537688122 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs537688122 come from?
GWAS Catalog, European journal of human genetics : EJHG 2023, PMID:36788145. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 112216Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others6Total11Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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