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Keloid scar (PheCode 701.4)

CSF2RB · rs536701773

Where this position leads

Condition: Keloid

rs536701773 Condition: Keloid Keloid Condition rs536701773 rs536701773 CSF2RB

What the study found

Who was studied 2,374 African American or Afro-Caribbean cases, 117,659 African American or Afro-Caribbean controls, 2,079 European ancestry cases, 444,929 European ancestry controls, 399 Hispanic or Latin American cases, 59,051 Hispanic or Latin American controls.

The effect Each copy of the C allele shifted the measure 2.32 lower (95% confidence interval 2.27-2.36); p = 7 × 10−12.

How common The C allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 22, band 22q12.3 — in an intron of CSF2RB.

What each result means

C/C Two copies of the version the research linked to Keloid scar (PheCode 701.4). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Keloid scar (PheCode 701.4). That is a smaller link than two copies.
T/T No copy of the version the research linked to Keloid scar (PheCode 701.4). This is the starting point the study compared everyone against.
Source

Questions about rs536701773

What is rs536701773?

rs536701773 is a single position in the genome, in or near the CSF2RB gene. Published research associates it with keloid scar (phecode 701.4). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs536701773 linked to?

On MyGeneLog this position is linked to Keloid. The research behind each link, and its sources, are set out on that condition page.

Does having rs536701773 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs536701773 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Keloid scar (PheCode 701.4) (rs536701773). MyGeneLog™. https://www.mygenelog.com/variants/rs536701773

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