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1-stearoyl-2-linoleoyl-GPI (18:0/18:2) levels

MYO5B · rs535211063

What the study found

Who was studied 6,136 Finnish ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.96 higher; p = 6 × 10−13.

Where it sits Chromosome 18, band 18q21.1 — in an intron of MYO5B.

What each result means

A/A No copy of the version the research linked to 1-stearoyl-2-linoleoyl-GPI (18:0/18:2) levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to 1-stearoyl-2-linoleoyl-GPI (18:0/18:2) levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to 1-stearoyl-2-linoleoyl-GPI (18:0/18:2) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs535211063

What is rs535211063?

rs535211063 is a single position in the genome, in or near the MYO5B gene. Published research associates it with 1-stearoyl-2-linoleoyl-gpi (18:0/18:2) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs535211063 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs535211063 come from?

GWAS Catalog, Nature communications 2022, PMID:35347128. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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1-stearoyl-2-linoleoyl-GPI (18:0/18:2) levels (rs535211063). MyGeneLog™. https://www.mygenelog.com/variants/rs535211063

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