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Cholesteryl esters to total lipids ratio in medium LDL

near MAP3K4-AS1 · rs532754706

What the study found

Who was studied 115,082 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.171 higher (95% confidence interval 0.14-0.2); p = 5 × 10−26.

How common The A allele had a frequency of about 98% in the people studied.

Where it sits Chromosome 6, band 6q26 — between genes, 81.4 kb from MAP3K4-AS1.

What each result means

A/A Two copies of the version the research linked to Cholesteryl esters to total lipids ratio in medium LDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Cholesteryl esters to total lipids ratio in medium LDL. That is a smaller link than two copies.
G/G No copy of the version the research linked to Cholesteryl esters to total lipids ratio in medium LDL. This is the starting point the study compared everyone against.
Source

Questions about rs532754706

What is rs532754706?

rs532754706 is a single position in the genome, in or near the near MAP3K4-AS1 gene. Published research associates it with cholesteryl esters to total lipids ratio in medium ldl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs532754706 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs532754706 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cholesteryl esters to total lipids ratio in medium LDL (rs532754706). MyGeneLog™. https://www.mygenelog.com/variants/rs532754706

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