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Who was studied 3,538 African American or Afro-Caribbean cases, 115,062 African American or Afro-Caribbean controls, 795 Hispanic or Latin American cases, 58,284 Hispanic or Latin American controls, 237 East Asian ancestry cases, 6,414 East Asian ancestry controls, 7,712 European ancestry cases, 435,461 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 1.75 lower (95% confidence interval 1.68-1.82); p = 7 × 10−13.
How common The G allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 1, band 1q31.3 — between genes, 129.1 kb from RNU6-983P.
What each result means
A/ANo copy of the version the research linked to Gouty arthropathy (PheCode 274.11). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Gouty arthropathy (PheCode 274.11). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Gouty arthropathy (PheCode 274.11). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs532582234
What is rs532582234?
rs532582234 is a single position in the genome, in or near the near RNU6-983P gene. Published research associates it with gouty arthropathy (phecode 274.11). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs532582234 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs532582234 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs532582234 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1211217Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)0Others7Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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