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Waist circumference

RP11-813B8.2 · rs532352152

Where this position leads

Condition: Waist Circumference

rs532352152 Condition: Waist Circumference Waist Circumference Condition rs532352152 rs532352152 RP11-813B8.2

What the study found

Who was studied 1,254 whole genome sequenced European ancestry individuals, 3,072 whole genome sequenced individuals, 41,450 European ancestry individuals, 397 Carlantino (founder/genetic isolate) individuals, 791 Friuli Venezia Giulia (founder/genetic isolate) individuals, 1,060 Mylopotamos (founder/genetic isolate) individuals, 887 Pomak (founder/genetic isolate) individuals, 1,754 Val Borbera (founder/genetic isolate) individuals; replicated in 206,737 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 1.12 higher (95% confidence interval 0.73-1.52); p = 2 × 10−8.

How common The A allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 8, band 8q21.13 — between genes, 129.8 kb from LINC01419.

What each result means

A/A Two copies of the version the research linked to Waist circumference. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Waist circumference. That is a smaller link than two copies.
G/G No copy of the version the research linked to Waist circumference. This is the starting point the study compared everyone against.
Source

Questions about rs532352152

What is rs532352152?

rs532352152 is a single position in the genome, in or near the RP11-813B8.2 gene. Published research associates it with waist circumference. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs532352152 linked to?

On MyGeneLog this position is linked to Waist Circumference. The research behind each link, and its sources, are set out on that condition page.

Does having rs532352152 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs532352152 come from?

GWAS Catalog, American journal of human genetics 2017, PMID:28552196. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Waist circumference (rs532352152). MyGeneLog™. https://www.mygenelog.com/variants/rs532352152

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