Sensitive

Biological Father: Bipolar Disorder

DIRC3 · rs529892601

Where this position leads

Condition: Bipolar Disorder

rs529892601 Condition: Bipolar Disorder Bipolar Disorder Condition rs529892601 rs529892601 DIRC3

What the study found

Who was studied 323 African American or Afro-Caribbean cases, 55,182 African American or Afro-Caribbean controls, 2,341 European ancestry cases, 313,327 European ancestry controls, 216 Hispanic or Latin American cases, 29,098 Hispanic or Latin American controls.

The effect Each copy of the C allele shifted the measure 2.34 lower (95% confidence interval 2.29-2.39); p = 1 × 10−11.

How common The C allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 2, band 2q35 — in an intron of DIRC3.

What each result means

C/C Two copies of the version the research linked to Biological Father: Bipolar Disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Biological Father: Bipolar Disorder. That is a smaller link than two copies.
T/T No copy of the version the research linked to Biological Father: Bipolar Disorder. This is the starting point the study compared everyone against.
Source

Questions about rs529892601

What is rs529892601?

rs529892601 is a single position in the genome, in or near the DIRC3 gene. Published research associates it with biological father: bipolar disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs529892601 linked to?

On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs529892601 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs529892601 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Biological Father: Bipolar Disorder (rs529892601). MyGeneLog™. https://www.mygenelog.com/variants/rs529892601

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