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Telomere length (principal component 1)

DDX19A · rs529549411

What the study found

Who was studied 438,351 Non-Finnish European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.105 higher (95% confidence interval 0.076-0.134); p = 1 × 10−12.

Where it sits Chromosome 16, band 16q22.1 — in an intron of DDX19A.

What each result means

C/C Two copies of the version the research linked to Telomere length (principal component 1). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Telomere length (principal component 1). That is a smaller link than two copies.
T/T No copy of the version the research linked to Telomere length (principal component 1). This is the starting point the study compared everyone against.
Source

Questions about rs529549411

What is rs529549411?

rs529549411 is a single position in the genome, in or near the DDX19A gene. Published research associates it with telomere length (principal component 1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs529549411 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs529549411 come from?

GWAS Catalog, Nature genetics 2024, PMID:39192095. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Telomere length (principal component 1) (rs529549411). MyGeneLog™. https://www.mygenelog.com/variants/rs529549411

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