Standard

Psoriasis (PheCode 696.4)

near SLC9A8 · rs528075

Where this position leads

Condition: Psoriasis

rs528075 Condition: Psoriasis Psoriasis Condition rs528075 rs528075 near SLC9A8

What the study found

Who was studied 16,283 European ancestry cases, 428,468 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0892 higher (95% confidence interval 0.066-0.112); p = 1 × 10−15.

How common The A allele had a frequency of about 54% in the people studied.

Where it sits Chromosome 20, band 20q13.13 — between genes, 2.9 kb from SLC9A8.

What each result means

A/A Two copies of the version the research linked to Psoriasis (PheCode 696.4). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Psoriasis (PheCode 696.4). That is a smaller link than two copies.
G/G No copy of the version the research linked to Psoriasis (PheCode 696.4). This is the starting point the study compared everyone against.
Source

Questions about rs528075

What is rs528075?

rs528075 is a single position in the genome, in or near the near SLC9A8 gene. Published research associates it with psoriasis (phecode 696.4). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs528075 linked to?

On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.

Does having rs528075 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs528075 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Psoriasis (PheCode 696.4) (rs528075). MyGeneLog™. https://www.mygenelog.com/variants/rs528075

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