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Immunoglobulin superfamily DCC subclass member 3:Extracellular domain levels

near IGDCC3 · rs525514

What the study found

Who was studied 3,506 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.204 higher (95% confidence interval 0.16-0.25); p = 5 × 10−17.

How common The C allele had a frequency of about 40% in the people studied.

Where it sits Chromosome 15, band 15q22.31 — between genes, 3.9 kb from IGDCC3.

What each result means

C/C Two copies of the version the research linked to Immunoglobulin superfamily DCC subclass member 3:Extracellular domain levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Immunoglobulin superfamily DCC subclass member 3:Extracellular domain levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Immunoglobulin superfamily DCC subclass member 3:Extracellular domain levels. This is the starting point the study compared everyone against.
Source

Questions about rs525514

What is rs525514?

rs525514 is a single position in the genome, in or near the near IGDCC3 gene. Published research associates it with immunoglobulin superfamily dcc subclass member 3:extracellular domain levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs525514 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs525514 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Immunoglobulin superfamily DCC subclass member 3:Extracellular domain levels (rs525514). MyGeneLog™. https://www.mygenelog.com/variants/rs525514

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