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Free cholesterol in medium HDL

near CPT1A · rs521913

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the T allele shifted the measure 0.01 mmol/L lower (95% confidence interval 0.01-0.01); p = 2 × 10−10.

Where it sits Chromosome 11, band 11q13.3 — between genes, 4.1 kb from CPT1A.

What each result means

C/C No copy of the version the research linked to Free cholesterol in medium HDL. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Free cholesterol in medium HDL. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Free cholesterol in medium HDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs521913

What is rs521913?

rs521913 is a single position in the genome, in or near the near CPT1A gene. Published research associates it with free cholesterol in medium hdl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs521913 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs521913 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Free cholesterol in medium HDL (rs521913). MyGeneLog™. https://www.mygenelog.com/variants/rs521913

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