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FASLG protein levels

LINC02098 · rs513365

Where this position leads

Condition: Celiac Disease

rs513365 Condition: Celiac Disease Celiac Disease Condition rs513365 rs513365 LINC02098

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0558 lower (95% confidence interval 0.045-0.066); p = 1 × 10−31.

How common The G allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 11, band 11q24.3 — in an intron of LINC02098.

What each result means

A/A No copy of the version the research linked to FASLG protein levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to FASLG protein levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to FASLG protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs513365

What is rs513365?

rs513365 is a single position in the genome, in or near the LINC02098 gene. Published research associates it with faslg protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs513365 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs513365 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs513365 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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FASLG protein levels (rs513365). MyGeneLog™. https://www.mygenelog.com/variants/rs513365

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