SLC22A12 · rs506338
Where this position leads
Condition: Gout
What the study found
Who was studied 8,868 Japanese ancestry individuals.
The effect Each copy of the C allele shifted the measure 0.229 lower (95% confidence interval 0.19-0.27); p = 2 × 10−31.
How common The C allele had a frequency of about 17% in the people studied.
Where it sits Chromosome 11, band 11q13.1 — in an intron of NRXN2.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs506338 is a single position in the genome, in or near the SLC22A12 gene. Published research associates it with urate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers), kidneys (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nat Genet 2010, PMID:20139978. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Urate levels (rs506338). MyGeneLog™. https://www.mygenelog.com/variants/rs506338