Standard

Atrial fibrillation (PheCode 427.21)

FRS2 · rs502736

Where this position leads

Condition: Atrial Fibrillation

rs502736 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs502736 rs502736 FRS2

What the study found

Who was studied 8,873 African American or Afro-Caribbean cases, 109,974 African American or Afro-Caribbean controls, 4,063 Hispanic or Latin American cases, 54,799 Hispanic or Latin American controls, 397 East Asian ancestry cases, 6,355 East Asian ancestry controls, 71,577 European ancestry cases, 366,195 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0532 higher (95% confidence interval 0.039-0.067); p = 2 × 10−14.

How common The A allele had a frequency of about 70% in the people studied.

Where it sits Chromosome 12, band 12q15 — in an intron of FRS2.

What each result means

A/A Two copies of the version the research linked to Atrial fibrillation (PheCode 427.21). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Atrial fibrillation (PheCode 427.21). That is a smaller link than two copies.
G/G No copy of the version the research linked to Atrial fibrillation (PheCode 427.21). This is the starting point the study compared everyone against.
Source

Questions about rs502736

What is rs502736?

rs502736 is a single position in the genome, in or near the FRS2 gene. Published research associates it with atrial fibrillation (phecode 427.21). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs502736 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs502736 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs502736 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atrial fibrillation (PheCode 427.21) (rs502736). MyGeneLog™. https://www.mygenelog.com/variants/rs502736

← See all variants