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Neutrophil count

BCL2L13 · rs5013026

Where this position leads

Condition: Blood Cell Counts

rs5013026 Condition: Blood Cell Counts Blood Cell Counts Condition rs5013026 rs5013026 BCL2L13

What the study found

Who was studied 170,702 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0206 higher (95% confidence interval 0.014-0.028); p = 8 × 10−9.

How common The T allele had a frequency of about 50% in the people studied.

Where it sits Chromosome 22, band 22q11.21 — in an intron of BCL2L13.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Neutrophil count — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Neutrophil count.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Neutrophil count compared to the general population.
Source

Questions about rs5013026

What is rs5013026?

rs5013026 is a single position in the genome, in or near the BCL2L13 gene. Published research associates it with neutrophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs5013026 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs5013026 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs5013026 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Neutrophil count (rs5013026). MyGeneLog™. https://www.mygenelog.com/variants/rs5013026

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