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Hypothyroidism

BAZ1A · rs4982208

Where this position leads

Condition: Hypothyroidism

rs4982208 Condition: Hypothyroidism Hypothyroidism Condition rs4982208 rs4982208 BAZ1A

What the study found

Who was studied 221,596 European ancestry cases, 1,564,466 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.0352 lower (95% confidence interval 0.025-0.046); p = 8 × 10−11.

How common The G allele had a frequency of about 14% in the people studied.

Where it sits Chromosome 14, band 14q13.1 — inside BAZ1A.

What each result means

A/A No copy of the version the research linked to Hypothyroidism. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Hypothyroidism. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Hypothyroidism. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4982208

What is rs4982208?

rs4982208 is a single position in the genome, in or near the BAZ1A gene. Published research associates it with hypothyroidism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4982208 linked to?

On MyGeneLog this position is linked to Hypothyroidism. The research behind each link, and its sources, are set out on that condition page.

Does having rs4982208 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4982208 come from?

GWAS Catalog, Nature genetics 2026, PMID:41644669. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hypothyroidism (rs4982208). MyGeneLog™. https://www.mygenelog.com/variants/rs4982208

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