Standard

Estimated glomerular filtration rate (creatinine)

near LINC02956 · rs4980598

What the study found

Who was studied 1,205,871 European ancestry individuals, 168,300 East Asian ancestry individuals, 63,553 African ancestry individuals, 23,509 Hispanic or Latin American individuals, 22,103 African American individuals, 21,791 Central Asian or South Asian ancestry individuals, 1,502 Middle Eastern ancestry individuals, 939 other admixed ancestry individuals, 602 Native American ancestry individuals, 150 Asian ancestry individuals, 339 individuals.

The effect Each copy of the C allele shifted the measure 8.29 z score lower; p = 1 × 10−16.

How common The C allele had a frequency of about 65% in the people studied.

Where it sits Chromosome 11, band 11q13.3 — between genes, 0.2 kb from LINC02956.

What each result means

C/C Two copies of the version the research linked to Estimated glomerular filtration rate (creatinine). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Estimated glomerular filtration rate (creatinine). That is a smaller link than two copies.
T/T No copy of the version the research linked to Estimated glomerular filtration rate (creatinine). This is the starting point the study compared everyone against.
Source

Questions about rs4980598

What is rs4980598?

rs4980598 is a single position in the genome, in or near the near LINC02956 gene. Published research associates it with estimated glomerular filtration rate (creatinine). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4980598 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4980598 come from?

GWAS Catalog, Nature genetics 2022, PMID:35710981. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Estimated glomerular filtration rate (creatinine) (rs4980598). MyGeneLog™. https://www.mygenelog.com/variants/rs4980598

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