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Urinary potassium to creatinine ratio

SLC4A7 · rs4973766

What the study found

Who was studied 218,435 European ancestry individuals; replicated in 109,178 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.021 lower (95% confidence interval 0.015-0.027); p = 6 × 10−14.

How common The T allele had a frequency of about 46% in the people studied.

Where it sits Chromosome 3, band 3p24.1 — between genes, 0.6 kb from SLC4A7.

What each result means

C/C No copy of the version the research linked to Urinary potassium to creatinine ratio. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Urinary potassium to creatinine ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Urinary potassium to creatinine ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4973766

What is rs4973766?

rs4973766 is a single position in the genome, in or near the SLC4A7 gene. Published research associates it with urinary potassium to creatinine ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4973766 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4973766 come from?

GWAS Catalog, Kidney international 2019, PMID:30910378. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urinary potassium to creatinine ratio (rs4973766). MyGeneLog™. https://www.mygenelog.com/variants/rs4973766

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