A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of End-stage renal disease in Type 1 diabetics compared to the general population.
A/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with End-stage renal disease in Type 1 diabetics.
T/TPublished research associates this genotype with typical/baseline likelihood of End-stage renal disease in Type 1 diabetics — no copies of the reported risk allele.
Journal of the American Society of Nephrology : JASN · 2013 · PMID 24029427
Questions about rs4972593
What is rs4972593?
rs4972593 is a single position in the genome, in or near the CDCA7 gene. Published research associates it with end-stage renal disease in type 1 diabetics. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4972593 linked to?
On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs4972593 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4972593 come from?
GWAS Catalog, J Am Soc Nephrol 2013, PMID:24029427. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.