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Total bilirubin levels

near LRRC28 · rs4965502

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0115 higher (95% confidence interval 0.008-0.015); p = 6 × 10−11.

Where it sits Chromosome 15, band 15q26.3 — between genes, 7.6 kb from LINC03080.

What each result means

C/C No copy of the version the research linked to Total bilirubin levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Total bilirubin levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Total bilirubin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4965502

What is rs4965502?

rs4965502 is a single position in the genome, in or near the near LRRC28 gene. Published research associates it with total bilirubin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4965502 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4965502 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total bilirubin levels (rs4965502). MyGeneLog™. https://www.mygenelog.com/variants/rs4965502

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