Sensitive

CD73 levels in metastatic colorectal cancer

LINC02535 · rs494688

Where this position leads

Condition: Colorectal Cancer

rs494688 Condition: Colorectal Cancer Colorectal Cancer Condition rs494688 rs494688 LINC02535

What the study found

Who was studied 869 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.61 lower (95% confidence interval -0.8--0.42); p = 2 × 10−9.

How common The A allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 6, band 6q14.3 — in an intron of LINC02535.

What each result means

A/A Two copies of the version the research linked to CD73 levels in metastatic colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to CD73 levels in metastatic colorectal cancer. That is a smaller link than two copies.
G/G No copy of the version the research linked to CD73 levels in metastatic colorectal cancer. This is the starting point the study compared everyone against.
Source

Questions about rs494688

What is rs494688?

rs494688 is a single position in the genome, in or near the LINC02535 gene. Published research associates it with cd73 levels in metastatic colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs494688 linked to?

On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs494688 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs494688 come from?

GWAS Catalog, BMC genomics 2024, PMID:38745123. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

CD73 levels in metastatic colorectal cancer (rs494688). MyGeneLog™. https://www.mygenelog.com/variants/rs494688

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