Standard

Triglycerides

ARMC2 · rs4945823

Where this position leads

Condition: High Triglycerides

rs4945823 Condition: High Triglycerides High Triglycerides Condition rs4945823 rs4945823 ARMC2

What the study found

Who was studied 343,992 European ancestry individuals, 111,667 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0183 higher (95% confidence interval 0.013-0.024); p = 4 × 10−10.

Where it sits Chromosome 6, band 6q21 — in a non-coding transcript of ARMC2.

What each result means

A/A Two copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
T/T No copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
Source

Questions about rs4945823

What is rs4945823?

rs4945823 is a single position in the genome, in or near the ARMC2 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4945823 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

Does having rs4945823 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4945823 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides (rs4945823). MyGeneLog™. https://www.mygenelog.com/variants/rs4945823

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