Standard

Pelvic organ prolapse

near RN7SKP297 · rs4944936

Where this position leads

Condition: Pelvic Organ Prolapse

rs4944936 Condition: Pelvic Organ Prolapse Pelvic Organ Prolapse Condition rs4944936 rs4944936 near RN7SKP2…

What the study found

Who was studied 771 Japanese ancestry female cases, 76,625 Japanese ancestry female controls, 28,086 European ancestry cases, 546,291 European ancestry controls.

The effect Each copy of the T allele carried 1.08 times the odds of Pelvic organ prolapse (95% confidence interval 1.056-1.102); p = 5 × 10−12.

Where it sits Chromosome 11, band 11q13.4 — between genes, 3.8 kb from RN7SKP297.

What each result means

C/C No copy of the version the research linked to Pelvic organ prolapse. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Pelvic organ prolapse. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Pelvic organ prolapse. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4944936

What is rs4944936?

rs4944936 is a single position in the genome, in or near the near RN7SKP297 gene. Published research associates it with pelvic organ prolapse. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4944936 linked to?

On MyGeneLog this position is linked to Pelvic Organ Prolapse. The research behind each link, and its sources, are set out on that condition page.

Does having rs4944936 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4944936 come from?

GWAS Catalog, Communications biology 2024, PMID:39349682. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Pelvic organ prolapse (rs4944936). MyGeneLog™. https://www.mygenelog.com/variants/rs4944936

← See all variants