Sensitive

Depression

DRD2 · rs4936272

Where this position leads

Condition: Endometriosis and Depression: Shared Genetics

rs4936272 Condition: Endometriosis and Depression: Shared Genetics Endometriosis and Depression: Share… Condition rs4936272 rs4936272 DRD2

What the study found

Who was studied 15,771 East Asian ancestry cases, 178,777 East Asian ancestry controls, 170,756 European ancestry cases, 329,443 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.00939 lower (95% confidence interval 0.0066-0.0122); p = 8 × 10−11.

How common The T allele had a frequency of about 40% in the people studied.

Where it sits Chromosome 11, band 11q23.2 — in an intron of DRD2.

What each result means

C/C No copy of the version the research linked to Depression. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Depression. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Depression. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4936272

What is rs4936272?

rs4936272 is a single position in the genome, in or near the DRD2 gene. Published research associates it with depression. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4936272 linked to?

On MyGeneLog this position is linked to Endometriosis and Depression: Shared Genetics. The research behind each link, and its sources, are set out on that condition page.

Does having rs4936272 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4936272 come from?

GWAS Catalog, JAMA psychiatry 2021, PMID:34586374. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Depression (rs4936272). MyGeneLog™. https://www.mygenelog.com/variants/rs4936272

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