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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 8,318 European ancestry individuals; replicated in (see Ahola-Olli 2017).
The effect
Each copy of the A allele shifted the measure 0.272 higher (95% confidence interval 0.26-0.28); p = 1 × 10−300.
Where it sits Chromosome 11, band 11q23.1 — in an intron of BCO2.
What each result means
A/ATwo copies of the version the research linked to Interleukin-18 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Interleukin-18 levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Interleukin-18 levels. This is the starting point the study compared everyone against.
PLoS genetics · 2020 · PMID 33227023 · open access
Questions about rs4935984
What is rs4935984?
rs4935984 is a single position in the genome, in or near the BCO2 gene. Published research associates it with interleukin-18 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4935984 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4935984 come from?
GWAS Catalog, PLoS genetics 2020, PMID:33227023. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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