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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 341,875 European ancestry individuals, 6,003 African ancestry individuals, 7,319 South Asian ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0689 lower (95% confidence interval 0.054-0.084); p = 5 × 10−19.
Where it sits Chromosome 1, band 1p32.3 — in an intron of USP24.
What each result means
C/CNo copy of the version the research linked to Low density lipoprotein cholesterol levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Low density lipoprotein cholesterol levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Low density lipoprotein cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs4927194
What is rs4927194?
rs4927194 is a single position in the genome, in or near the USP24 gene. Published research associates it with low density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4927194 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4927194 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Low density lipoprotein cholesterol levels (rs4927194). MyGeneLog™. https://www.mygenelog.com/variants/rs4927194