Standard
Hand grip strength
GLIS1 · rs4926611
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hand grip strength compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hand grip strength.
T/T
Published research associates this genotype with typical/baseline likelihood of Hand grip strength — no copies of the reported risk allele.
Source
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
Willems SM,
Wright DJ,
Day FR,
Trajanoska K,
Joshi PK,
Morris JA,
Matteini AM,
Garton FC,
Grarup N,
Oskolkov N,
Thalamuthu A,
Mangino M
and 64 more — show all
Liu J,
Demirkan A,
Lek M,
Xu L,
Wang G,
Oldmeadow C,
Gaulton KJ,
Lotta LA,
Miyamoto-Mikami E,
Rivas MA,
White T,
Loh PR,
Aadahl M,
Amin N,
Attia JR,
Austin K,
Benyamin B,
Brage S,
Cheng YC,
Cięszczyk P,
Derave W,
Eriksson KF,
Eynon N,
Linneberg A,
Lucia A,
Massidda M,
Mitchell BD,
Miyachi M,
Murakami H,
Padmanabhan S,
Pandey A,
Papadimitriou I,
Rajpal DK,
Sale C,
Schnurr TM,
Sessa F,
Shrine N,
Tobin MD,
Varley I,
Wain LV,
Wray NR,
Lindgren CM,
MacArthur DG,
Waterworth DM,
McCarthy MI,
Pedersen O,
Khaw KT,
Kiel DP,
Pitsiladis Y,
Fuku N,
Franks PW,
North KN,
van Duijn CM,
Mather KA,
Hansen T,
Hansson O,
Spector T,
Murabito JM,
Richards JB,
Rivadeneira F,
Langenberg C,
Perry JRB,
Wareham NJ,
Scott RA
Nature communications · 2017 · PMID 29313844 · open access
Questions about rs4926611
What is rs4926611?
rs4926611 is a single position in the genome, in or near the GLIS1 gene. Published research associates it with hand grip strength. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4926611 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4926611 come from?
GWAS Catalog, Nat Commun 2017, PMID:29313844. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants