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Sensitive

Bipolar disorder

NFIX · rs4926298

Where this position leads

Condition: Bipolar Disorder

rs4926298 Condition: Bipolar Disorder Bipolar Disorder Condition rs4926298 rs4926298 NFIX

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Bipolar disorder — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Bipolar disorder.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Bipolar disorder compared to the general population.
Source
A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder
Ikeda M, Takahashi A, Kamatani Y, Okahisa Y, Kunugi H, Mori N, Sasaki T, Ohmori T, Okamoto Y, Kawasaki H, Shimodera S, Kato T
and 28 more — show all
Yoneda H, Yoshimura R, Iyo M, Matsuda K, Akiyama M, Ashikawa K, Kashiwase K, Tokunaga K, Kondo K, Saito T, Shimasaki A, Kawase K, Kitajima T, Matsuo K, Itokawa M, Someya T, Inada T, Hashimoto R, Inoue T, Akiyama K, Tanii H, Arai H, Kanba S, Ozaki N, Kusumi I, Yoshikawa T, Kubo M, Iwata N
Molecular psychiatry · 2018 · PMID 28115744 · open access

Questions about rs4926298

What is rs4926298?

rs4926298 is a single position in the genome, in or near the NFIX gene. Published research associates it with bipolar disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4926298 linked to?

On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs4926298 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4926298 come from?

GWAS Catalog, Mol Psychiatry 2017, PMID:28115744. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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