Standard

estimated glomerular filtration rate (eGFR, maximum, inv-norm transformed)

near SMCR2 · rs4925094

What the study found

Who was studied 110,850 African American or Afro-Caribbean individuals, 55,242 Hispanic or Latin American individuals, 6,249 East Asian ancestry individuals, 398,886 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0214 higher (95% confidence interval 0.016-0.027); p = 4 × 10−16.

How common The G allele had a frequency of about 47% in the people studied.

Where it sits Chromosome 17, band 17p11.2 — between genes, 8.3 kb from SMCR2.

What each result means

A/A No copy of the version the research linked to estimated glomerular filtration rate (eGFR, maximum, inv-norm transformed). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to estimated glomerular filtration rate (eGFR, maximum, inv-norm transformed). That is a smaller link than two copies.
G/G Two copies of the version the research linked to estimated glomerular filtration rate (eGFR, maximum, inv-norm transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4925094

What is rs4925094?

rs4925094 is a single position in the genome, in or near the near SMCR2 gene. Published research associates it with estimated glomerular filtration rate (egfr, maximum, inv-norm transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4925094 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4925094 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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estimated glomerular filtration rate (eGFR, maximum, inv-norm transformed) (rs4925094). MyGeneLog™. https://www.mygenelog.com/variants/rs4925094

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