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Brain imaging measurements

near THBS1 · rs4924345

What the study found

Who was studied 8,428 British ancestry individuals; replicated in 4,386 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.353 higher (95% confidence interval 0.31-0.4); p = 3 × 10−53.

How common The C allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 15, band 15q14 — between genes, 92.9 kb from LINC02915.

What each result means

A/A No copy of the version the research linked to Brain imaging measurements. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Brain imaging measurements. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Brain imaging measurements. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4924345

What is rs4924345?

rs4924345 is a single position in the genome, in or near the near THBS1 gene. Published research associates it with brain imaging measurements. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4924345 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4924345 come from?

GWAS Catalog, Nature 2018, PMID:30305740. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Brain imaging measurements (rs4924345). MyGeneLog™. https://www.mygenelog.com/variants/rs4924345

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