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Neuroticism (MTAG)

near RNU7-165P · rs4918814

Where this position leads

Condition: Neuroticism

rs4918814 Condition: Neuroticism Neuroticism Condition rs4918814 rs4918814 near RNU7-16…

What the study found

Who was studied 168,105 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0177 lower (95% confidence interval 0.012-0.024); p = 1 × 10−8.

How common The C allele had a frequency of about 28% in the people studied.

Where it sits Chromosome 10, band 10q25.3 — between genes, 6.9 kb from RNU7-165P.

What each result means

A/A No copy of the version the research linked to Neuroticism (MTAG). This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Neuroticism (MTAG). That is a smaller link than two copies.
C/C Two copies of the version the research linked to Neuroticism (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4918814

What is rs4918814?

rs4918814 is a single position in the genome, in or near the near RNU7-165P gene. Published research associates it with neuroticism (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4918814 linked to?

On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.

Does having rs4918814 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4918814 come from?

GWAS Catalog, Nature genetics 2018, PMID:29292387. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Neuroticism (MTAG) (rs4918814). MyGeneLog™. https://www.mygenelog.com/variants/rs4918814

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