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LDL cholesterol levels

near TECTB · rs4918732

What the study found

Who was studied 58,701 Korean ancestry individuals.

The effect Each copy of the A allele shifted the measure 1.33 lower (95% confidence interval 0.95-1.71); p = 6 × 10−12.

Where it sits Chromosome 10, band 10q25.2 — between genes, 23.6 kb from TECTB.

What each result means

A/A Two copies of the version the research linked to LDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to LDL cholesterol levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to LDL cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs4918732

What is rs4918732?

rs4918732 is a single position in the genome, in or near the near TECTB gene. Published research associates it with ldl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4918732 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4918732 come from?

GWAS Catalog, Biomedicines 2022, PMID:35884923. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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LDL cholesterol levels (rs4918732). MyGeneLog™. https://www.mygenelog.com/variants/rs4918732

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