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Insomnia

TMEM161B-DT · rs4916907

Where this position leads

Condition: Insomnia

rs4916907 Condition: Insomnia Insomnia Condition rs4916907 rs4916907 TMEM161B-DT

What the study found

Who was studied 651,923 European ancestry males, 679,087 European ancestry females.

The effect Each copy of the G allele carried 1.08 times the odds of Insomnia (95% confidence interval 1.06-1.10); p = 3 × 10−11.

How common The G allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 5, band 5q14.3 — in an intron of TMEM161B-DT.

What each result means

G/G Two copies of the version the research linked to Insomnia. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Insomnia. That is a smaller link than two copies.
T/T No copy of the version the research linked to Insomnia. This is the starting point the study compared everyone against.
Source

Questions about rs4916907

What is rs4916907?

rs4916907 is a single position in the genome, in or near the TMEM161B-DT gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4916907 linked to?

On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.

Does having rs4916907 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4916907 come from?

GWAS Catalog, Nature genetics 2019, PMID:30804565. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insomnia (rs4916907). MyGeneLog™. https://www.mygenelog.com/variants/rs4916907

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