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Who was studied 426,824 British ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0113 lower (95% confidence interval 0.0076-0.015); p = 2 × 10−9.
How common The G allele had a frequency of about 61% in the people studied.
Where it sits Chromosome 8, band 8q24.22 — in an intron of ZFAT.
What each result means
G/GTwo copies of the version the research linked to Heel bone mineral density. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Heel bone mineral density. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Heel bone mineral density. This is the starting point the study compared everyone against.
Nature genetics · 2019 · PMID 30598549 · open access
Questions about rs4909323
What is rs4909323?
rs4909323 is a single position in the genome, in or near the ZFAT gene. Published research associates it with heel bone mineral density. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4909323 linked to?
On MyGeneLog this position is linked to Heel Bone Mineral Density. The research behind each link, and its sources, are set out on that condition page.
Does having rs4909323 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4909323 come from?
GWAS Catalog, Nature genetics 2019, PMID:30598549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 1822113Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others13Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Heel bone mineral density (rs4909323). MyGeneLog™. https://www.mygenelog.com/variants/rs4909323