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Morningness

near LIN52 · rs4899502

What the study found

Who was studied 434,835 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.016 lower (95% confidence interval 0.012-0.02); p = 2 × 10−11.

How common The A allele had a frequency of about 69% in the people studied.

Where it sits Chromosome 14, band 14q24.3 — between genes, 1.7 kb from LIN52.

What each result means

A/A Two copies of the version the research linked to Morningness. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Morningness. That is a smaller link than two copies.
G/G No copy of the version the research linked to Morningness. This is the starting point the study compared everyone against.
Source

Questions about rs4899502

What is rs4899502?

rs4899502 is a single position in the genome, in or near the near LIN52 gene. Published research associates it with morningness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4899502 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4899502 come from?

GWAS Catalog, Nature genetics 2019, PMID:30804565. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Morningness (rs4899502). MyGeneLog™. https://www.mygenelog.com/variants/rs4899502

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