Sensitive

Behcet's disease

IFNGR1 · rs4896243

Where this position leads

Condition: Behcet's Disease

rs4896243 Condition: Behcet's Disease Behcet's Disease Condition rs4896243 rs4896243 IFNGR1

What the study found

Who was studied 2,344 Turkish ancestry cases, 1,920 Turkish ancestry controls, 437 European ancestry cases, 3,325 European ancestry controls, 312 East Asian ancestry cases, 398 East Asian ancestry controls, 104 Tunisian ancestry cases, 142 Tunisian ancestry controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 2 × 10−9.

Where it sits Chromosome 6, band 6q23.3 — between genes, 3.8 kb from IFNGR1.

What each result means

C/C Two copies of the version the research linked to Behcet's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Behcet's disease. That is a smaller link than two copies.
T/T No copy of the version the research linked to Behcet's disease. This is the starting point the study compared everyone against.
Source

Questions about rs4896243

What is rs4896243?

rs4896243 is a single position in the genome, in or near the IFNGR1 gene. Published research associates it with behcet's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4896243 linked to?

On MyGeneLog this position is linked to Behcet's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs4896243 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4896243 come from?

GWAS Catalog, Arthritis & rheumatology (Hoboken, N.J.) 2021, PMID:33393726. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Behcet's disease (rs4896243). MyGeneLog™. https://www.mygenelog.com/variants/rs4896243

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