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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 39,533 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0524 lower (95% confidence interval 0.039-0.066); p = 1 × 10−15.
Where it sits Chromosome 6, band 6q22.31 — in an intron of TPD52L1.
What each result means
G/GTwo copies of the version the research linked to Putamen iron levels (R2* MRI). That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Putamen iron levels (R2* MRI). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Putamen iron levels (R2* MRI). This is the starting point the study compared everyone against.
Neurobiology of disease · 2024 · PMID 38789058 · open access
Questions about rs4895687
What is rs4895687?
rs4895687 is a single position in the genome, in or near the TPD52L1 gene. Published research associates it with putamen iron levels (r2* mri). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4895687 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4895687 come from?
GWAS Catalog, Neurobiology of disease 2024, PMID:38789058. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Putamen iron levels (R2* MRI) (rs4895687). MyGeneLog™. https://www.mygenelog.com/variants/rs4895687