Sensitive

Coronary atherosclerosis (PheCode 411.4)

near RNU6-758P · rs4888372

Where this position leads

Condition: Coronary Artery Disease

rs4888372 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs4888372 rs4888372 near RNU6-75…

What the study found

Who was studied 124,302 European ancestry cases, 300,039 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.0458 lower (95% confidence interval 0.035-0.057); p = 6 × 10−23.

How common The G allele had a frequency of about 43% in the people studied.

Where it sits Chromosome 16, band 16q23.1 — between genes, 7.1 kb from RNU6-758P.

What each result means

A/A No copy of the version the research linked to Coronary atherosclerosis (PheCode 411.4). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Coronary atherosclerosis (PheCode 411.4). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Coronary atherosclerosis (PheCode 411.4). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs4888372

What is rs4888372?

rs4888372 is a single position in the genome, in or near the near RNU6-758P gene. Published research associates it with coronary atherosclerosis (phecode 411.4). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4888372 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs4888372 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4888372 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Coronary atherosclerosis (PheCode 411.4) (rs4888372). MyGeneLog™. https://www.mygenelog.com/variants/rs4888372

← See all variants