Immunoglobulin superfamily containing leucine-rich repeat protein 2 levels
CCDC33 · rs4887135
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,917 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.186 lower (95% confidence interval 0.13-0.24); p = 1 × 10−11.
How common The A allele had a frequency of about 52% in the people studied.
Where it sits Chromosome 15, band 15q24.1 — in an intron of CCDC33.
What each result means
A/ATwo copies of the version the research linked to Immunoglobulin superfamily containing leucine-rich repeat protein 2 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Immunoglobulin superfamily containing leucine-rich repeat protein 2 levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Immunoglobulin superfamily containing leucine-rich repeat protein 2 levels. This is the starting point the study compared everyone against.
Nature communications · 2021 · PMID 34857772 · open access
Questions about rs4887135
What is rs4887135?
rs4887135 is a single position in the genome, in or near the CCDC33 gene. Published research associates it with immunoglobulin superfamily containing leucine-rich repeat protein 2 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4887135 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4887135 come from?
GWAS Catalog, Nature communications 2021, PMID:34857772. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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