Systolic blood pressure x alcohol consumption interaction (2df test)
COX5A · rs4886640
1 28211022227Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity1Meta AI10Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 63,608 European ancestry drinkers, 10,193 African American or Afro-Caribbean heavy drinkers, 2,441 Asian ancestry drinkers, 5,084 Hispanic or Latin American drinkers, 27,494 European ancestry non-drinkers, 11,224 African American or Afro-Caribbean non-drinkers, 9,924 Asian ancestry non-drinkers, 3,387 Hispanic or Latin American non-drinkers; replicated in 238,002 European ancestry drinkers, 2,280 African American drinkers, 54,081 Asian ancestry drinkers, 6,452 Hispanic drinkers, 43,316 European ancestry non-drinkers, 2,761 African American non-drinkers, 86,945 Asian ancestry non-drinkers, 6,925 Hispanic non-drinkers.
The effect
The reported allele is A; the catalogue records no effect size
; p = 6 × 10−16.
How common The A allele had a frequency of about 51% in the people studied.
Where it sits Chromosome 15, band 15q24.2 — in an intron of COX5A.
What each result means
A/ATwo copies of the version the research linked to Systolic blood pressure x alcohol consumption interaction (2df test). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Systolic blood pressure x alcohol consumption interaction (2df test). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Systolic blood pressure x alcohol consumption interaction (2df test). This is the starting point the study compared everyone against.
rs4886640 is a single position in the genome, in or near the COX5A gene. Published research associates it with systolic blood pressure x alcohol consumption interaction (2df test). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4886640 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs4886640 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4886640 come from?
GWAS Catalog, PLoS One 2018, PMID:29912962. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 28211022227Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity1Meta AI10Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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