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Atrial fibrillation (MTAG)

FBRSL1 · rs4883571

Where this position leads

Condition: Atrial Fibrillation

rs4883571 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs4883571 rs4883571 FBRSL1

What the study found

Who was studied 296,021 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 5.56 z-score higher; p = 3 × 10−8.

How common The A allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 12, band 12q24.33 — in an intron of FBRSL1.

What each result means

A/A Two copies of the version the research linked to Atrial fibrillation (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Atrial fibrillation (MTAG). That is a smaller link than two copies.
G/G No copy of the version the research linked to Atrial fibrillation (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs4883571

What is rs4883571?

rs4883571 is a single position in the genome, in or near the FBRSL1 gene. Published research associates it with atrial fibrillation (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs4883571 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs4883571 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4883571 come from?

GWAS Catalog, NPJ genomic medicine 2025, PMID:41022758. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atrial fibrillation (MTAG) (rs4883571). MyGeneLog™. https://www.mygenelog.com/variants/rs4883571

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