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Uterine leiomyomata

LNX1 · rs4864806

What the study found

Who was studied 38,466 European ancestry cases, 329,437 European ancestry controls.

The effect Each copy of the A allele carried 1.17 times the odds of Uterine leiomyomata (95% confidence interval 1.13-1.2); p = 5 × 10−21.

Where it sits Chromosome 4, band 4q12 — in an intron of LNX1.

What each result means

A/A Two copies of the version the research linked to Uterine leiomyomata. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Uterine leiomyomata. That is a smaller link than two copies.
G/G No copy of the version the research linked to Uterine leiomyomata. This is the starting point the study compared everyone against.
Source

Questions about rs4864806

What is rs4864806?

rs4864806 is a single position in the genome, in or near the LNX1 gene. Published research associates it with uterine leiomyomata. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4864806 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4864806 come from?

GWAS Catalog, Nature communications 2023, PMID:36726022. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Uterine leiomyomata (rs4864806). MyGeneLog™. https://www.mygenelog.com/variants/rs4864806

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