SHROOM3 · rs4859682
Where this position leads
Condition: Kidney Function
What the study found
Who was studied 9,049 European ancestry individuals.
The effect Each copy of the A allele shifted the measure 0.96 lower (95% confidence interval 0.65-1.27); p = 2 × 10−9.
How common The A allele had a frequency of about 45% in the people studied.
Where it sits Chromosome 4, band 4q21.1 — in an intron of SHROOM3.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs4859682 is a single position in the genome, in or near the SHROOM3 gene. Published research associates it with glomerular filtration rate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.
Subjects that appear in the title or abstract of the same papers as this rsID include kidneys (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, J Hum Genet 2013, PMID:23535967. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Glomerular filtration rate (rs4859682). MyGeneLog™. https://www.mygenelog.com/variants/rs4859682