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Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
What the study found
Who was studied 2,758 European ancestry individuals; replicated in 18,554 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.07 lower (95% confidence interval 0.05-0.09); p = 2 × 10−13.
How common The G allele had a frequency of about 40% in the people studied.
Where it sits Chromosome 1, band 1q42.13 — in an intron of GALNT2.
What each result means
A/ANo copy of the version the research linked to HDL cholesterol. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to HDL cholesterol. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to HDL cholesterol. That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs4846914
What is rs4846914?
rs4846914 is a single position in the genome, in or near the GALNT2 gene. Published research associates it with hdl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs4846914 linked to?
On MyGeneLog this position is linked to High Triglycerides, Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs4846914?
Subjects that appear in the title or abstract of the same papers as this rsID include cholesterol and blood fats (4 papers), blood sugar and insulin (3 papers), heart and circulation (3 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs4846914 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4846914 come from?
GWAS Catalog, Nat Genet 2008, PMID:18193044. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
4 5032127222227Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity2Meta AI7Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others27Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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