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Pulmonary embolism

LINC02182 · rs4843804

What the study found

Who was studied 622 Han Chinese ancestry cases, 8,853 Han Chinese ancestry controls; replicated in 646 Han Chinese ancestry cases, 8,810 Han Chinese ancestry controls.

The effect Each copy of the A allele carried 0.35 times the odds of Pulmonary embolism (95% confidence interval 0.26-0.47); p = 2 × 10−12.

How common The A allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 16, band 16q24.2 — in an intron of LINC02182.

What each result means

A/A Two copies of the version the research linked to Pulmonary embolism. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Pulmonary embolism. That is a smaller link than two copies.
G/G No copy of the version the research linked to Pulmonary embolism. This is the starting point the study compared everyone against.
Source

Questions about rs4843804

What is rs4843804?

rs4843804 is a single position in the genome, in or near the LINC02182 gene. Published research associates it with pulmonary embolism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs4843804 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4843804 come from?

GWAS Catalog, BMC medicine 2023, PMID:37076872. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Pulmonary embolism (rs4843804). MyGeneLog™. https://www.mygenelog.com/variants/rs4843804

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