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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 4,198 European ancestry individuals, 2,574 African American or Afro-Caribbean, Hispanic or Latin American, Sub-Saharan African ancestry individuals.
The effect
The reported allele is T; the catalogue records no effect size
; p = 3 × 10−11.
Where it sits Chromosome 15, band 15q25.2 — in an intron of ADAMTSL3.
What each result means
C/CNo copy of the version the research linked to Cranial vault shape (segment 2). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Cranial vault shape (segment 2). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Cranial vault shape (segment 2). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2023 · PMID 37973980 · open access
Questions about rs4842918
What is rs4842918?
rs4842918 is a single position in the genome, in or near the ADAMTSL3 gene. Published research associates it with cranial vault shape (segment 2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs4842918 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs4842918 come from?
GWAS Catalog, Nature communications 2023, PMID:37973980. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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